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Sufferers who will be presently receiving drugs that happen to be sturdy inducers or inhibitors of CYP3A4 are usually not suitable. Sturdy inducers or inhibitors of CYP3A4 ought to be prevented from 14 times just before enrollment to the end from the analyze.Experimental: Dose expansion_sub-population 2_higher dose of niraparib MTDs and/or candidat